Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages

The alternatively activated macrophage phenotype induced by IL-10 is called M2c. Adenosine is an endogenous purine nucleoside that accumulates in the extracellular space in response to metabolic disturbances, hypoxia, inflammation, physical damage, or apoptosis. As adenosine is known to regulate cla...

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Main Authors: Koscsó, Balázs, Csóka, Balázs, Kókai, Endre, Németh, Zoltán H., Pacher, Pál, Virág, László, Leibovich, S. Joseph, Haskó, György
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2013
Teme:
Inflammation, Extracellular Mediators, & Effector Molecules
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828607/
https://ncbi.nlm.nih.gov/pubmed/23922379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0113043
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