Tonic Activation of Bax Primes Neural Progenitors for Rapid Apoptosis through a Mechanism Preserved in Medulloblastoma

Commitment to survival or apoptosis within expanding progenitor populations poses distinct risks and benefits to the organism. We investigated whether specialized mechanisms regulate apoptosis in mouse neural progenitors and in the progenitor-derived brain tumor medulloblastoma. Here, we identified...

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Autores principales: Crowther, Andrew J., Gama, Vivian, Bevilacqua, Ariana, Chang, Sha X., Yuan, Hong, Deshmukh, Mohanish, Gershon, Timothy R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828463/
https://ncbi.nlm.nih.gov/pubmed/24227720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2602-13.2013
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