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Acute Activation, Desensitization and Smoldering Activation of Human Acetylcholine Receptors

The behavioral effects of nicotine and other nicotinic agonists are mediated by AChRs in the brain. The relative contribution of acute activation versus chronic desensitization of AChRs is unknown. Sustained “smoldering activation” occurs over a range of agonist concentrations at which activated and...

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Detalhes bibliográficos
Main Authors: Campling, Barbara G., Kuryatov, Alexander, Lindstrom, Jon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828267/
https://ncbi.nlm.nih.gov/pubmed/24244538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079653
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