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Small Molecule Inhibitors of Integrin α2β1

Interactions between the integrin, α2β1, and extracellular matrix (ECM), particularly collagen, play a pivotal role in platelet adhesion and thrombus formation. Platelets interact with collagen in the subendothelial matrix that is exposed by vascular damage. To evaluate the potential of α2β1 inhibit...

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Detalles Bibliográficos
Main Authors: Choi, Sungwook, Vilaire, Gaston, Marcinkiewicz, Cezary, Winkler, Jeffrey D., Bennett, Joel S., DeGrado, William F.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828121/
https://ncbi.nlm.nih.gov/pubmed/17915848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm070252b
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