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K-RAS and P53 Mutations in Association with COX-2 and Htert Expression and Clinico-Pathological Status of Nsclc Patients

We evaluated the occurrence of mutations in P53, K-RAS, COX-2, expression of COX-2 and hTERT and relations among clinicopathological signs. P53 mutations were identified in 34.4% of tumours, the majority of them occurring in SCC (squamous cell carcinoma, 55.6%). K-RAS was mutated in 12.2% of NSCLC t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stražišar, Mojca, Rott, Tomaž, Glavač, Damjan
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827803/
https://ncbi.nlm.nih.gov/pubmed/18957720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/232743
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