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Development of Asymmetric Deacylative Allylation

Herein we present the development of asymmetric deacylative allylation of ketone enolates. The reaction directly couples readily available ketone pronucleophiles with allylic alcohols using facile retro-Claisen cleavage to form reactive intermediates in situ. The simplicity and robustness of the rea...

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Autors principals: Grenning, Alexander J., Van Allen, Christie K., Maji, Tapan, Lang, Simon B., Tunge, Jon A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827786/
https://ncbi.nlm.nih.gov/pubmed/23734611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo400793a
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