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Thioredoxin 1 is Essential for Sodium Sulfide-Mediated Cardioprotection in the Setting of Heart Failure
OBJECTIVE: The aim of this study was to determine if thioredoxin-1 (Trx1) mediates the cardioprotective effects of hydrogen sulfide (H(2)S) in a model of ischemic-induced heart failure. APPROACH/RESULTS: Mice with a cardiac-specific overexpression of a dominant negative mutant of Trx1 (Tg-DN-Trx1) a...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3827725/ https://ncbi.nlm.nih.gov/pubmed/23349187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300484 |
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