Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent Manner

BACKGROUND: Therapeutic strategies aimed at increasing hydrogen sulfide (H(2)S) levels exert cytoprotective effects in various models of cardiovascular injury. However, the underlying mechanism(s) responsible for this protection remain to be fully elucidated. Nuclear-factor-E2-related factor-2 (Nrf2...

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Pubblicato in:Circ Heart Fail
Autori principali: Shimizu, Yuuki, Nicholson, Chad K., Lambert, Jonathan P., Barr, Larry A., Kuek, Nicholas, Herszenhaut, David, Tan, Lin, Murohara, Toyoaki, Hansen, Jason M., Husain, Ahsan, Naqvi, Nawazish, Calvert, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826721/
https://ncbi.nlm.nih.gov/pubmed/27056879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.002368
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