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Hydrogen sulfide preconditions the db/db diabetic mouse heart against ischemia-reperfusion injury by activating Nrf2 signaling in an Erk-dependent manner

Hydrogen sulfide (H(2)S) therapy protects nondiabetic animals in various models of myocardial injury, including acute myocardial infarction and heart failure. Here, we sought to examine whether H(2)S therapy provides cardioprotection in the setting of type 2 diabetes. H(2)S therapy in the form of so...

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Detalhes bibliográficos
Main Authors: Peake, Bridgette F., Nicholson, Chad K., Lambert, Jonathan P., Hood, Rebecca L., Amin, Hena, Amin, Sana, Calvert, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652093/
https://ncbi.nlm.nih.gov/pubmed/23479260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00796.2012
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