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Mechanisms and function of substrate recruitment by F-box proteins

S phase kinase-associated protein 1 (SKP1)–cullin 1 (CUL1)–F-box protein (SCF) ubiquitin ligase complexes use a family of F-box proteins as substrate adaptors to mediate the degradation of a large number of regulatory proteins involved in diverse processes. The dysregulation of SCF complexes and the...

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Détails bibliographiques
Auteurs principaux: Skaar, Jeffrey R., Pagan, Julia K., Pagano, Michele
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827686/
https://ncbi.nlm.nih.gov/pubmed/23657496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3582
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