Structure-Guided Discovery of New Deaminase Enzymes

A substantial challenge for genomic enzymology is the reliable annotation for proteins of unknown function. Described here is an interrogation of uncharacterized enzymes from the amidohydrolase superfamily using a structure-guided approach that integrates bioinformatics, computational biology and mo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hitchcock, Daniel S., Fan, Hao, Kim, Jungwook, Vetting, Matthew, Hillerich, Brandan, Seidel, Ronald D., Almo, Steven C., Shoichet, Brian K., Sali, Andrej, Raushel, Frank M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827683/
https://ncbi.nlm.nih.gov/pubmed/23968233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4066078
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