Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis.
Human complement factor H controls spontaneous activation of complement in plasma and appears to play a role in distinguishing host cells from activators of the alternative pathway of complement. In both mice and humans, the protein is composed of 20 homologous short consensus repeat (SCR) domains....
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1996
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38272/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10996 |
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