Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis.
Human complement factor H controls spontaneous activation of complement in plasma and appears to play a role in distinguishing host cells from activators of the alternative pathway of complement. In both mice and humans, the protein is composed of 20 homologous short consensus repeat (SCR) domains....
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38272/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10996 |
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