Structural Variation-Associated Expression Changes Are Paralleled by Chromatin Architecture Modifications

Copy number variants (CNVs) influence the expression of genes that map not only within the rearrangement, but also to its flanks. To assess the possible mechanism(s) underlying this “neighboring effect”, we compared intrachromosomal interactions and histone modifications in cell lines of patients af...

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Detalhes bibliográficos
Main Authors: Gheldof, Nele, Witwicki, Robert M., Migliavacca, Eugenia, Leleu, Marion, Didelot, Gérard, Harewood, Louise, Rougemont, Jacques, Reymond, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827143/
https://ncbi.nlm.nih.gov/pubmed/24265791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079973
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