Cytosine modifications modulate the chromatin architecture of transcriptional enhancers

Epigenetic mechanisms are believed to play key roles in the establishment of cell-specific transcription programs. Accordingly, the modified bases 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) have been observed in DNA of genomic regulatory regions such as enhancers, and oxidation of 5mC...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Res
Main Authors: Mahé, Elise A., Madigou, Thierry, Sérandour, Aurélien A., Bizot, Maud, Avner, Stéphane, Chalmel, Frédéric, Palierne, Gaëlle, Métivier, Raphaël, Salbert, Gilles
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453328/
https://ncbi.nlm.nih.gov/pubmed/28396520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.211466.116
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