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A deubiquitinase negatively regulates retro-translocation of nonubiquitinated substrates
Endoplasmic reticulum (ER) membrane–bound E3 ubiquitin ligases promote ER-associated degradation (ERAD) by ubiquitinating a retro-translocated substrate that reaches the cytosol from the ER, targeting it to the proteasome for destruction. Recent findings implicate ERAD-associated deubiquitinases (DU...
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| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society for Cell Biology
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826992/ https://ncbi.nlm.nih.gov/pubmed/24068323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-06-0332 |
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