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Electrostatics of cysteine residues in proteins: Parameterization and validation of a simple model

One of the most popular and simple models for the calculation of pK(a)s from a protein structure is the semi-macroscopic electrostatic model MEAD. This model requires empirical parameters for each residue to calculate pK(a)s. Analysis of current, widely used empirical parameters for cysteine residue...

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Autori principali: Salsbury, Freddie R., Poole, Leslie B., Fetrow, Jacquelyn S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826958/
https://ncbi.nlm.nih.gov/pubmed/22777874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24142
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