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FBXW5 controls centrosome number

Regulatory mechanisms to prevent centriole overduplication during the cell cycle are not completely understood. In this issue, FBXW5 is shown to control the degradation of the centriole assembly factor HsSAS-6. Moreover, the study proposes that FBXW5 is a substrate of both PLK4 and APC/C, two establ...

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Dettagli Bibliografici
Autori principali: Pagan, Julia, Pagano, Michele
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826792/
https://ncbi.nlm.nih.gov/pubmed/21808243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2312
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