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Autophagy controls centrosome number by degrading Cep63
Centrosome number is associated with the chromosome segregation and genomic stability. The ubiquitin–proteasome system is considered to be the main regulator of centrosome number. However, here we show that autophagy also regulates the number of centrosomes. Autophagy-deficient cells carry extra cen...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473638/ https://ncbi.nlm.nih.gov/pubmed/27869116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13508 |
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