Complement-Activating IgM Enhances the Humoral but Not the T Cell Immune Response in Mice

IgM antibodies specific for a certain antigen can enhance antibody responses when administered together with this antigen, a process believed to require complement activation by IgM. However, recent data show that a knock-in mouse strain, Cμ13, which only produces IgM unable to activate complement,...

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Bibliografiske detaljer
Main Authors: Ding, Zhoujie, Bergman, Anna, Rutemark, Christian, Ouchida, Rika, Ohno, Hiroshi, Wang, Ji-Yang, Heyman, Birgitta
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826713/
https://ncbi.nlm.nih.gov/pubmed/24250831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081299
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