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Intranasal Delivery of Neural Stem Cells: A CNS-specific, Non-invasive Cell-based Therapy for Experimental Autoimmune Encephalomyelitis

The therapeutic potential of adult neural stem cells (aNSCs) has been shown in EAE, an animal model of MS, administered by either i.c.v. or i.v. injection. However, i.c.v. is an invasive approach, while the i.v. route of aNSCs is associated with a non-specific immune suppression in the periphery. He...

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Bibliographic Details
Main Authors: Wu, Shuai, Li, Ke, Yan, Yaping, Gran, Bruno, Han, Yan, Zhou, Fang, Guan, Yang-Tai, Rostami, Abdolmohamad, Zhang, Guang-Xian
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826545/
https://ncbi.nlm.nih.gov/pubmed/24244890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000142
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