Autotaxin Production of Lysophosphatidic Acid Mediates Allergic Asthmatic Inflammation

Rationale: Bioactive lipid mediators, derived from membrane lipid precursors, are released into the airway and airspace where they bind high-affinity cognate receptors and may mediate asthma pathogenesis. Lysophosphatidic acid (LPA), a bioactive lipid mediator generated by the enzymatic activity of...

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Hlavní autoři: Park, Gye Young, Lee, Yong Gyu, Berdyshev, Evgeny, Nyenhuis, Sharmilee, Du, Jian, Fu, Panfeng, Gorshkova, Irina A., Li, Yongchao, Chung, Sangwoon, Karpurapu, Manjula, Deng, Jing, Ranjan, Ravi, Xiao, Lei, Jaffe, H. Ari, Corbridge, Susan J., Kelly, Elizabeth A. B., Jarjour, Nizar N., Chun, Jerold, Prestwich, Glenn D., Kaffe, Eleanna, Ninou, Ioanna, Aidinis, Vassilis, Morris, Andrew J., Smyth, Susan S., Ackerman, Steven J., Natarajan, Viswanathan, Christman, John W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826286/
https://ncbi.nlm.nih.gov/pubmed/24050723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201306-1014OC
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