Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines

INTRODUCTION: Thoracic malignancies and human breast cancer (HBC) continue to be aggressive solid tumors that are poor responders to the existing conventional standard chemotherapeutic approaches. Malignant pleural mesothelioma (MPM) is an asbestos-related tumor of the thoracic pleura that lacks eff...

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Autors principals: Wang, Ying, Rishi, Arun K., Puliyappadamba, Vineshkumar T., Sharma, Sunita, Yang, Huanjie, Tarca, Adi, Dou, Q. Ping, Lonardo, Fulvio, Ruckdeschel, John C., Pass, Harvey I., Wali, Anil
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826182/
https://ncbi.nlm.nih.gov/pubmed/19960346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1181-8
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