Disulfiram Suppresses Growth of the Malignant Pleural Mesothelioma Cells in Part by Inducing Apoptosis

Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibitor of aldehyde dehydrogenase is a Food and Drug Administration approved agent for treatment of alcoholism. Copper complexed DSF (DSF-Cu) also possesses anti-tumor and chemosensitizing properties; however, its...

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Detalhes bibliográficos
Main Authors: Cheriyan, Vino T., Wang, Ying, Muthu, Magesh, Jamal, Shazia, Chen, Di, Yang, Huanjie, Polin, Lisa A., Tarca, Adi L., Pass, Harvey I., Dou, Q. Ping, Sharma, Sunita, Wali, Anil, Rishi, Arun K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972204/
https://ncbi.nlm.nih.gov/pubmed/24690739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093711
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