Disulfiram Suppresses Growth of the Malignant Pleural Mesothelioma Cells in Part by Inducing Apoptosis

Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibitor of aldehyde dehydrogenase is a Food and Drug Administration approved agent for treatment of alcoholism. Copper complexed DSF (DSF-Cu) also possesses anti-tumor and chemosensitizing properties; however, its...

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Main Authors: Cheriyan, Vino T., Wang, Ying, Muthu, Magesh, Jamal, Shazia, Chen, Di, Yang, Huanjie, Polin, Lisa A., Tarca, Adi L., Pass, Harvey I., Dou, Q. Ping, Sharma, Sunita, Wali, Anil, Rishi, Arun K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972204/
https://ncbi.nlm.nih.gov/pubmed/24690739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093711
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