Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis.

Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibitor of aldehyde dehydrogenase is a Food and Drug Administration approved agent for treatment of alcoholism. Copper complexed DSF (DSF-Cu) also possesses anti-tumor and chemosensitizing properties; however, its...

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Detalhes bibliográficos
Main Authors: Vino T Cheriyan, Ying Wang, Magesh Muthu, Shazia Jamal, Di Chen, Huanjie Yang, Lisa A Polin, Adi L Tarca, Harvey I Pass, Q Ping Dou, Sunita Sharma, Anil Wali, Arun K Rishi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3972204?pdf=render
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