Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice.

The tet regulatory system in which doxycycline (dox) acts as an inducer of specifically engineered RNA polymerase II promoters was transferred into transgenic mice. Tight control and a broad range of regulation spanning up to five orders of magnitude were monitored dependent on the dox concentration...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kistner, A, Gossen, M, Zimmermann, F, Jerecic, J, Ullmer, C, Lübbert, H, Bujard, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38261/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10933
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!