A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice.
A system for tetracycline-regulated inducible gene expression was described recently which relies on constitutive expression of a tetracycline-controlled transactivator (tTA) fusion protein combining the tetracycline repressor and the transcriptional activation domain of VP16 [Gossen, M. & Bujard, H...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7604026/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.14.6522 |
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