Finding the missing heritability in pediatric obesity: the contribution of genome-wide complex trait analysis

Known single-nucleotide polymorphisms (SNPs) explain <2% of the variation in body mass index (BMI) despite the evidence of >50% heritability from twin and family studies, a phenomenon termed ‘missing heritability'. Using DNA alone for unrelated individuals, a novel method (in a software p...

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Bibliografske podrobnosti
Main Authors: Llewellyn, C H, Trzaskowski, M, Plomin, R, Wardle, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Short Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826033/
https://ncbi.nlm.nih.gov/pubmed/23528754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2013.30
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