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Aneuploidy and chromosomal instability: a vicious cycle driving cellular evolution and cancer genome chaos

Aneuploidy and chromosomal instability frequently co-exist, and aneuploidy is recognized as a direct outcome of chromosomal instability. However, chromosomal instability is widely viewed as a consequence of mutations in genes involved in DNA replication, chromosome segregation and cell cycle checkpo...

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Main Authors: Potapova, Tamara A, Zhu, Jin, Li, Rong
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825812/
https://ncbi.nlm.nih.gov/pubmed/23709119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-013-9436-6
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