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Aneuploidy and chromosomal instability: a vicious cycle driving cellular evolution and cancer genome chaos
Aneuploidy and chromosomal instability frequently co-exist, and aneuploidy is recognized as a direct outcome of chromosomal instability. However, chromosomal instability is widely viewed as a consequence of mutations in genes involved in DNA replication, chromosome segregation and cell cycle checkpo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825812/ https://ncbi.nlm.nih.gov/pubmed/23709119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-013-9436-6 |
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