Caricamento...

Glutathione Depletion by L-Buthionine-S,R-Sulfoximine Induces Apoptosis of Cardiomyocytes through Activation of PKC-δ

In the present study, we investigated the effect of intracellular glutathione (GSH) depletion in heart-derived H9c2 cells and its mechanism. L-buthionine-S,R-sulfoximine (BSO) induced the depletion of cellular GSH, and BSO-induced reactive oxygen species (ROS) production was inhibited by glutathione...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kim, Young-Ae, Kim, Mi-Young, Jung, Yi-Sook
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Society of Applied Pharmacology 2013
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825199/
https://ncbi.nlm.nih.gov/pubmed/24244823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2013.065
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !