Depletion of tumour versus normal tissue glutathione by buthionine sulfoximine.

We have investigated in detail the effects of buthionine sulfoximine (BSO), a selective glutathione (GSH) depleting agent, on the GSH contents of a number of normal tissues and three experimental tumours in mice. Significant variations in the rate and degree of GSH depletion and recovery were observ...

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Autores principales: Lee, F. Y., Allalunis-Turner, M. J., Siemann, D. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1987
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001684/
https://ncbi.nlm.nih.gov/pubmed/3620316
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