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Sigma-1 receptor chaperones regulate the secretion of brain-derived neurotrophic factor

The sigma-1 receptor (Sig-1R) is a novel endoplasmic reticulum (ER) molecular chaperone that regulates protein folding and degradation. The Sig-1R activation by agonists is known to improve memory, promote cell survival, and exert an antidepressant-like action in animals. Cutamesine (SA4503), a sele...

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Bibliografiska uppgifter
Huvudupphovsmän: Fujimoto, Michiko, Hayashi, Teruo, Urfer, Roman, Mita, Shiro, Su, Tsung-Ping
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824965/
https://ncbi.nlm.nih.gov/pubmed/22337473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21549
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