The Lifetime of UDP-galactose:Ceramide Galactosyltransferase Is Controlled by a Distinct Endoplasmic Reticulum-associated Degradation (ERAD) Regulated by Sigma-1 Receptor Chaperones

The glycosphingolipid biosynthesis is initiated by monoglycosylation of ceramides, the action of which is catalyzed either by UDP-glucose:ceramide glucosyltransferase or by UDP-galactose:ceramide galactosyltransferase (CGalT). CGalT is expressed predominantly at the endoplasmic reticulum (ER) of oli...

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Detalhes bibliográficos
Main Authors: Hayashi, Teruo, Hayashi, Eri, Fujimoto, Michiko, Sprong, Hein, Su, Tsung-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522309/
https://ncbi.nlm.nih.gov/pubmed/23105111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380444
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