Modest phenotypic improvements in ASA-deficient mice with only one UDP-galactose:ceramide-galactosyltransferase gene

BACKGROUND: Arylsulfatase A (ASA)-deficient mice are a model for the lysosomal storage disorder metachromatic leukodystrophy. This lipidosis is characterised by the lysosomal accumulation of the sphingolipid sulfatide. Storage of this lipid is associated with progressive demyelination. We have mated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Franken, S, Wittke, D, Mansson, JE, D'Hooge, R, De Deyn, PP, Lüllmann-Rauch, R, Matzner, U, Gieselmann, V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564137/
https://ncbi.nlm.nih.gov/pubmed/16893448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-5-21
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados