Modest phenotypic improvements in ASA-deficient mice with only one UDP-galactose:ceramide-galactosyltransferase gene

BACKGROUND: Arylsulfatase A (ASA)-deficient mice are a model for the lysosomal storage disorder metachromatic leukodystrophy. This lipidosis is characterised by the lysosomal accumulation of the sphingolipid sulfatide. Storage of this lipid is associated with progressive demyelination. We have mated...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Franken, S, Wittke, D, Mansson, JE, D'Hooge, R, De Deyn, PP, Lüllmann-Rauch, R, Matzner, U, Gieselmann, V
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564137/
https://ncbi.nlm.nih.gov/pubmed/16893448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-5-21
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi