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Sigma-1 receptor chaperones regulate the secretion of brain-derived neurotrophic factor
The sigma-1 receptor (Sig-1R) is a novel endoplasmic reticulum (ER) molecular chaperone that regulates protein folding and degradation. The Sig-1R activation by agonists is known to improve memory, promote cell survival, and exert an antidepressant-like action in animals. Cutamesine (SA4503), a sele...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824965/ https://ncbi.nlm.nih.gov/pubmed/22337473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21549 |
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