EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells

FAK is a non-receptor tyrosine kinase contributing to migration and proliferation downstream of integrin and/or growth factor receptor signaling of normal and malignant cells. In addition to well-characterized tyrosine phosphorylations, FAK is phosphorylated on several serines, whose role is not yet...

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Главные авторы: Rea, K, Sensi, M, Anichini, A, Canevari, S, Tomassetti, A
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2013
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824663/
https://ncbi.nlm.nih.gov/pubmed/24091658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.353
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