Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes

Oxidative stress contributes to dysfunction of glial cells in the optic nerve head (ONH). However, the biological basis of the precise functional role of mitochondria in this dysfunction is not fully understood. Coenzyme Q10 (CoQ(10)), an essential cofactor of the electron transport chain and a pote...

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Detalhes bibliográficos
Main Authors: Noh, Y H, Kim, K-Y, Shim, M S, Choi, S-H, Choi, S, Ellisman, M H, Weinreb, R N, Perkins, G A, Ju, W-K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824651/
https://ncbi.nlm.nih.gov/pubmed/24091663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.341
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