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Calcineurin-mediated Dephosphorylation of eNOS at Serine 116 Affects eNOS Enzymatic Activity Indirectly by Facilitating c-Src Binding and Tyrosine 83 Phosphorylation
It has been shown previously that phosphorylation of the endothelial nitric oxide synthase (eNOS) at serine 116 (S116) under basal conditions suppresses eNOS enzymatic activity in endothelial cells. It has also been shown that vascular endothelial growth factor (VEGF) treatment of endothelial cells...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824616/ https://ncbi.nlm.nih.gov/pubmed/23727078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2013.05.004 |
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