Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma Multiforme through de-repression of Bcl-xL translation

Glioblastoma multiforme (GBM) is the most common and aggressive form of tumor of the central nervous system. Despite significant efforts to improve treatments, patient survival rarely exceeds 18 months largely due to the highly chemoresistant nature of these tumors. Importantly, misregulation of the...

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Main Authors: Liwak, Urszula, Jordan, Lindsay E., Von-Holt, Sally Davidson, Singh, Poonam, Hanson, Jennifer E.L., Lorimer, Ian A., Roncaroli, Federico, Holcik, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2013
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824522/
https://ncbi.nlm.nih.gov/pubmed/23965755
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