Different Head Environments in Tarantula Thick Filaments Support a Cooperative Activation Process

Myosin filaments from many muscles are activated by phosphorylation of their regulatory light chains (RLCs). Structural analysis of relaxed tarantula thick filaments shows that the RLCs of the interacting free and blocked myosin heads are in different environments. This and other data suggested a ph...

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Autors principals: Sulbarán, Guidenn, Biasutto, Antonio, Alamo, Lorenzo, Riggs, Claire, Pinto, Antonio, Méndez, Franklin, Craig, Roger, Padrón, Raúl
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
Matèries:
Molecular Machines, Motors and Nanoscale Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824520/
https://ncbi.nlm.nih.gov/pubmed/24209856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.09.001
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