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A molecular model of phosphorylation-based activation and potentiation of tarantula muscle thick filaments

Myosin filaments from many muscles are activated by phosphorylation of their regulatory light chains (RLCs). To elucidate the structural mechanism of activation, we have studied RLC phosphorylation in tarantula thick filaments, whose high resolution structure is known. In the relaxed state, tarantul...

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Detalhes bibliográficos
Main Authors: Brito, Reicy, Alamo, Lorenzo, Lundberg, Ulf, Guerrero, José R., Pinto, Antonio, Sulbarán, Guidenn, Gawinowicz, Mary Ann, Craig, Roger, Padrón, Raúl
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215904/
https://ncbi.nlm.nih.gov/pubmed/21959262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.09.017
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