Different Head Environments in Tarantula Thick Filaments Support a Cooperative Activation Process

Myosin filaments from many muscles are activated by phosphorylation of their regulatory light chains (RLCs). Structural analysis of relaxed tarantula thick filaments shows that the RLCs of the interacting free and blocked myosin heads are in different environments. This and other data suggested a ph...

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Bibliografische gegevens
Hoofdauteurs: Sulbarán, Guidenn, Biasutto, Antonio, Alamo, Lorenzo, Riggs, Claire, Pinto, Antonio, Méndez, Franklin, Craig, Roger, Padrón, Raúl
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2013
Onderwerpen:
Molecular Machines, Motors and Nanoscale Biophysics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824520/
https://ncbi.nlm.nih.gov/pubmed/24209856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.09.001
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