Different Head Environments in Tarantula Thick Filaments Support a Cooperative Activation Process

Myosin filaments from many muscles are activated by phosphorylation of their regulatory light chains (RLCs). Structural analysis of relaxed tarantula thick filaments shows that the RLCs of the interacting free and blocked myosin heads are in different environments. This and other data suggested a ph...

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Bibliografiske detaljer
Main Authors: Sulbarán, Guidenn, Biasutto, Antonio, Alamo, Lorenzo, Riggs, Claire, Pinto, Antonio, Méndez, Franklin, Craig, Roger, Padrón, Raúl
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2013
Fag:
Molecular Machines, Motors and Nanoscale Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824520/
https://ncbi.nlm.nih.gov/pubmed/24209856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.09.001
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