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MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survival
The molecular mechanisms that underlie T-cell quiescence are poorly understood. In the present study, we report a primary immunodeficiency phenotype associated with MST1 deficiency and primarily characterized by a progressive loss of naive T cells. The in vivo consequences include recurrent bacteria...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824282/ https://ncbi.nlm.nih.gov/pubmed/22174160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-378364 |
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