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Adenosine Monophosphate–Activated Protein Kinase Is Required for Pulmonary Artery Smooth Muscle Cell Survival and the Development of Hypoxic Pulmonary Hypertension
Human pulmonary artery smooth muscle cells (HPASMCs) express both adenosine monophosphate–activated protein kinase (AMPK) α(1) and α(2). We investigated the distinct roles of AMPK α(1) and α(2) in the survival of HPASMCs during hypoxia and hypoxia-induced pulmonary hypertension (PH). The exposure of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824043/ https://ncbi.nlm.nih.gov/pubmed/23668615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0446OC |
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