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Adenosine Monophosphate–Activated Protein Kinase Is Required for Pulmonary Artery Smooth Muscle Cell Survival and the Development of Hypoxic Pulmonary Hypertension
Human pulmonary artery smooth muscle cells (HPASMCs) express both adenosine monophosphate–activated protein kinase (AMPK) α(1) and α(2). We investigated the distinct roles of AMPK α(1) and α(2) in the survival of HPASMCs during hypoxia and hypoxia-induced pulmonary hypertension (PH). The exposure of...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Thoracic Society
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824043/ https://ncbi.nlm.nih.gov/pubmed/23668615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0446OC |
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