Panobinostat Enhances Cytarabine and Daunorubicin Sensitivities in AML Cells through Suppressing the Expression of BRCA1, CHK1, and Rad51

Acute myeloid leukemia (AML) remains a challenging disease to treat and urgently requires new therapies to improve its treatment outcome. In this study, we investigated the molecular mechanisms underlying the cooperative antileukemic activities of panobinostat and cytarabine or daunorubicin (DNR) in...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Xie, Chengzhi, Drenberg, Christina, Edwards, Holly, Caldwell, J. Timothy, Chen, Wei, Inaba, Hiroto, Xu, Xuelian, Buck, Steven A., Taub, Jeffrey W., Baker, Sharyn D., Ge, Yubin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823972/
https://ncbi.nlm.nih.gov/pubmed/24244429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079106
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items