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Ethanol Inhibits Activation of NLRP3 and AIM2 Inflammasomes in Human Macrophages–A Novel Anti-Inflammatory Action of Alcohol

OBJECTIVE: In the pathogenesis of coronary atherosclerosis, local macrophage-driven inflammation and secretion of proinflammatory cytokines, interleukin-1β (IL-1β) in particular, are recognized as key factors. Moderate alcohol consumption is associated with a reduced risk of coronary artery disease...

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Detalhes bibliográficos
Main Authors: Nurmi, Katariina, Virkanen, Juhani, Rajamäki, Kristiina, Niemi, Katri, Kovanen, Petri T., Eklund, Kari K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823849/
https://ncbi.nlm.nih.gov/pubmed/24244322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078537
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