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NF-κB-Induced IL-6 Ensures STAT3 Activation and Tumor Aggressiveness in Glioblastoma

Glioblastoma (GBM) is the most aggressive, neurologically destructive and deadly tumor of the central nervous system (CNS). In GBM, the transcription factors NF-κB and STAT3 are aberrantly activated and associated with tumor cell proliferation, survival, invasion and chemoresistance. In addition, co...

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書誌詳細
主要な著者: McFarland, Braden C., Hong, Suk W., Rajbhandari, Rajani, Twitty, George B., Gray, G. Kenneth, Yu, Hao, Benveniste, Etty N., Nozell, Susan E.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823708/
https://ncbi.nlm.nih.gov/pubmed/24244348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078728
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