NF-κB-Induced IL-6 Ensures STAT3 Activation and Tumor Aggressiveness in Glioblastoma

Glioblastoma (GBM) is the most aggressive, neurologically destructive and deadly tumor of the central nervous system (CNS). In GBM, the transcription factors NF-κB and STAT3 are aberrantly activated and associated with tumor cell proliferation, survival, invasion and chemoresistance. In addition, co...

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Bibliografiska uppgifter
Huvudupphovsmän: McFarland, Braden C., Hong, Suk W., Rajbhandari, Rajani, Twitty, George B., Gray, G. Kenneth, Yu, Hao, Benveniste, Etty N., Nozell, Susan E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823708/
https://ncbi.nlm.nih.gov/pubmed/24244348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078728
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